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The Muasher Center
for Fertility and IVF
8501 Arlington Boulevard, Suite 500
Fairfax, Virginia 22031

Ph. 703.876.6311
Fx. 703.876.6317

• Hear What Infertility Pioneer Dr. Howard W. Jones Jr. Has to Say
• Press Release
• Hear What Patients Say

Success Rates, In Vitro Fertilization (IVF), Donor Egg

IVF

Success rates in IVF are dependent on many factors, such as the age of the female, ovarian reserve (ability to produce multiple eggs), history of failed IUI and/or IVF treatments in the past, smoking, and the quality of the sperm. Younger women are usually more successful than older ones, with a noticeable drop in pregnancy rates after the age of 35. Couples who are undergoing their first IVF attempt or have had a successful IVF pregnancy in the past have better chances than those who have had multiple failed IVF treatments. Smokers (male/female) are less successful than non-smokers. Women with poor ovarian reserve (high day 3 FSH value and/or abnormal Clomiphene Citrate challenge test) are in general less successful than those with good reserve.

At our center, we do not exclude women based on their FSH levels (unless it is clearly menopausal) and we believe in working with all situations no matter how difficult they are. In fact, we treat a good percentage of patients that have been rejected or who have had previous failures. We believe in providing an opportunity for a successful pregnancy for all couples no matter how good or poor their chances are.

At our center, approximately 40% of couples will have excess embryos that are available for cryopreservation, if the couple elects to freeze them.

During the last year (January 2007 - December 2007)

• 1. The clinical pregnancy rate per fresh IVF transfers was 41% (34/83)
• 2. The clinical pregnancy rate per Frozen Embryo transfer using non-donor eggs was 50% (4/8) and for those using donor eggs was 50% (4/8).

Please keep in mind that this is an average rate and some couples will have a higher rate and some will have a lower rate depending on their particular situation. Also, in our center, approximately 10% of the stimulated cycles are cancelled prior to egg retrieval done to lack of recruitment of follicles.

Minimal Stimulation IVF Protocol

We recently began offering the Minimal Stimulation IVF Protocol for those couples who do not have insurance coverage or who otherwise cannot afford standard IVF. The number of eggs produced with the Minimal Stimulation Protocol is less than standard IVF therefore the success rates are usually lower. The documented success rates for the Minimal Stimulation Protocol are 30-35% per embryo transfer (Fertility Sterility 2002;78:1068-72). During the last year (January 2007-December 2007) the clinical pregnancy rate per fresh transfer was 40% (6/15). Please note that there were three cycles that were cancelled prior to egg retrieval and 4 other cycles that did not have an embryo transfer during the same time.

Donor Egg

Our donor egg program is one of the most successful treatments in infertility and In-Vitro Fertilization. Success rates can be expected to be greater that 60% in terms of clinical pregnancies. The primary reason is that the eggs are collected from young donors (ages 21-32) who are carefully screened and selected in order to assure a safe and successful treatment process.

The clinical pregnancy rate per fresh transfer was 56% (5/9) from January 2007 to December 2007. Keep in mind that this is from fresh transfers only and the cumulative pregnancy rate (fresh and/or frozen) will be higher with the transfer of frozen embryos in these women.

IUI

Our IUI success rates are extremely good. In general, anovulatory women, women with unexplained infertility, and younger women respond better to this treatment. We treat all age groups with IUI. Dr Muasher has several combinations of ovarian stimulation for IUI, from Clomid to a combination of Clomid and injectable FSH preparations, and injectable FSH alone. He will individualize treatments to your needs.

During the last year (January 2007-December 2007) the clinical pregnancy rate from IUI was 33% (42/128). This is an average rate for all patients, all ages, and different indications for treatment. Please remember that some patients will have a better prognosis and some others will have worse prognosis depending on the individual situation.